2049597 - Error Message 'System <RFC_DEST> cannot be reached raised' in Marketing Plan

When accessing any marketing plan object such as a marketing plan, a campaign or a trade promotion the following error message is raised:

Marketing Application in CRM WEB UI

'System <RFC_DEST> cannot be reached; CRM_MKTPL 182; CRM_MKTPL182; Define Target Systems (ERP, BW, SEM, cPro); BW; BI; CRM_MKTPL_CHECK_RFCDEST; CL_CRM_MKTPL_IMG_ACCESS=>GET_SEM_CENTRAL_SETTINGS; SMOFPARSFA; MKTPLBW; MKTPLBWRFC; System <RFC_DEST> nicht erreichbar; Zielsysteme (ERP, BI, SEM, CPRO) definieren; , KBA , CRM-MKT-MPL , Marketing Planner , CRM-ANA-PS , Planning Services , CRM-MKT-MPL-ST-KFP , Key Figure Planning , CRM-MKT-MPL-ST-BI , BI Interface , CRM-MKT-MPL-CPG , Marketing Planning and Campaign Management , Problem