2049836 - "Problem occurred while creating JCO client destination" error in the UWL

When accessing the Universal Worklist iView in the portal, a message Cannot connect to provider is shown:

Clicking in the Display Connection Status link (shown below) shows further details regarding the error:

Upon clicking in the link, the following error appears for a connector whose type is WebFlowConnector:
“Problem occured while creating JCO client for destination: <system_alias>”

When checking the default trace of the server right after the problem has been recreated (see SAP Note 1596214), following error can be found (only the relevant trace excerpt):

...
Problem occured while creating JCO client for destination: <systemalias>:com.sap.conn.jco.JCoException: (106) JCO_ERROR_RESOURCE: Destination <systemalias>$WebFlowConnector does not exist
...
Exception in verifying existence of function module <uwl function module> for system <systemalias>:java.lang.Exception: Problem occured while creating JCO client for destination: <systemalias>
...
Caught java.lang.Exception: Problem occured while creating JCO client for destination: <systemalias>
at com.sap.netweaver.bc.uwl.utils.r3.R3SystemInfo.createJCoDestination(R3SystemInfo.java:84)
…

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• SAP Universal Worklist (UWL)
• SAP Enterprise Portal 
• SAP NetWeaver Application Server Java

SAP NetWeaver 7.0 ; SAP NetWeaver 7.3 ; SAP NetWeaver 7.4 ; SAP NetWeaver 7.5 ; SAP NetWeaver Application Server for Java 7.1 ; SAP NetWeaver Application Server for Java 7.2 ; SAP enhancement package 1 for SAP NetWeaver 7.0 ; SAP enhancement package 1 for SAP NetWeaver 7.3 ; SAP enhancement package 1 for SAP NetWeaver Application Server for Java 7.1 ; SAP enhancement package 2 for SAP NetWeaver 7.0 ; SAP enhancement package 3 for SAP NetWeaver 7.0

ocurred, occured, exception , KBA , EP-BC-UWL , Universal Worklist , Problem