2286976 - ENQU: "R13=> Error in program flow" message in the System Log

The "Error in program flow" message appears in the System Log (SM21 transaction)

The ENQ work process died and in its developer trace file (dev_w<nr>) the following error messages appear:

M  ***LOG R13=> ThCheckRequest, wrong address () [thRequest.c  4806]
M  in_ThErrHandle: 1
M  *** ERROR => ThCheckRequest: wrong address (step TH_WORK_SYNC, thRc ERROR-CORE-INTERNAL_ERROR, action RESTART_WP, level 1) [thxxh
M  {root-id=6CAE8B0240381ED5B7D8E541983A95D1}_{conn-id=00000000000000000000000000000000}_0
M  ThIErrHandle: set thRc ERROR-CORE-INTERNAL_ERROR for T79_U1928_M0

or this one:

E  *** ERROR => EnqueQueryRemote: Response opcode 1 expect(3) [enxxhead.c   4906] 
E  {root-id=566F9C6C84021EE5B4903679EF5CC846}_{conn-id=00000000000000000000000000000000}_0 

As the ENQ work process is constantly dying, many work processes are in status "on Hold" running program "SAPLSENA" in the dialog instances.

The system runs with clasical Enqueue implementation (in the Central Instance) and several dialog instances

SAPLSENA, Error in program flow, R13, ENQUE_READ, ENQUE_READ2, Transfer error while reading lock entries , KBA , BC-CST-EQ , Enqueue , BC-ABA , ABAP Runtime Environment - ABAP Language Issues Only , Problem