2482145 - JCO_ERROR_SERVER_STARTUP: Server startup failed

The RFC Sender Communication Channel in PI is in error and you can see the following exception:

com.sap.mw.jco.JCO$Exception: (129) JCO_ERROR_SERVER_STARTUP: Server startup failed at XXX XXXX XXXX XXXX XXX
This is caused by either a) erroneous server settings, b) the backend system has been shutdown, c) network problems. Will try next startup in xx seconds.
Could not start server: Connect to SAP gateway failed Connect parameters....
parameters: TPNAME=XXXX GWHOST=XXXX GWSERV=XXXXX ERROR hostname 'xxxx' unknown TIME XX XX XX XX RELEASE XXX COMPONENT NI (network interface)
VERSION XX RC -2 MODULE nixxhl.cpp LINE XXX DETAIL NiHLGetNodeAddr: hostname cached as unknown COUNTER 1

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• PI Release Independent
• SAP NetWeaver
• SAP Process Integration

SAP NetWeaver 2004 ; SAP NetWeaver 7.0 ; SAP NetWeaver 7.1 ; SAP NetWeaver 7.2 ; SAP NetWeaver 7.3 ; SAP NetWeaver 7.4 ; SAP NetWeaver 7.5 ; SAP enhancement package 1 for SAP NetWeaver 7.0 ; SAP enhancement package 1 for SAP NetWeaver 7.3 ; SAP enhancement package 1 for SAP NetWeaver Application Server for ABAP 7.1 ; SAP enhancement package 2 for SAP NetWeaver 7.0 ; SAP enhancement package 3 for SAP NetWeaver 7.0

RFC, PI, PO, XI, CC, Sender, SM59, JRA, GatewayServer, Process Integration 7.0, PI 7.0, PI 7.01, PI 7.02, Process Integration 7.10, PI 7.10, Process Integration 7.11, PI 7.11, Process Integration 7.30, PI 7.30, Process Integration 7.31, PI 7.31, Process Orchestration 7.40, PI 7.40, PO 7.40, Process Orchestration 7.50, PI 7.50, PO 7.50, NetWeaver, XI , KBA , BC-XI-CON-RFC , RFC Adapter , Problem