2538900 - 404 Not Found error when refreshing Mapping Cache

When trying to Refresh the Mapping Cache, the following error occurs:

404 Not Found
Error: Requested resource does not exist.

In the defaultTrace file, you can see the following exception:

Cannot process an HTTP request to servlet [MappingRuntimeRefreshServlet] in [run] web application.
[EXCEPTION]
javax.servlet.ServletException: com.sap.aii.utilxi.hmi.api.HmiCoreException: Connection to system xiServer using application ibrun lost. Detailed information: Exception while openning http url connection to "https://<host>:<port>/run/value_mapping_cache/int?"! Message is: Internal error in method createConnection(URL aUrl) of class com.sap.aii.utilxi.hmi.api.JdkHttpURLConnectionFactory. Detailed information: !"http".equals(aUrl.getProtocol())

• PI Release Independent
• SAP NetWeaver
• SAP Process Integration

Mapping runtime cache, mapping runtime, mapping, MappingCache, 404, run/MappingCache/refresh?mode=F, runtime cache, Process Integration 7.0, PI 7.0, PI 7.01, PI 7.02, Process Integration 7.10, PI 7.10, Process Integration 7.11, PI 7.11, Process Integration 7.30, PI 7.30, Process Integration 7.31, PI 7.31, Process Orchestration 7.40, PI 7.40, PO 7.40, Process Orchestration 7.50, PI 7.50, PO 7.50, NetWeaver, XI , KBA , BC-XI-IBC-MAP , Mapping , Problem