3315873 - Problems with stacked TRFN scenarios with mixed DTP Runtime

During DTP creation in HANA Studio/Eclipse a similar message is shown:

Resource DTPA & could not be successfully created.

OR

The DTP activation fails with a similar error message:

: The transformations of the path are incompatible
Object DTPA & is not consistent
Transformation path of DTP & is invalid. DTP maintenance not possible.

OR

In a BW/4HANA 2021 system which is on Support Package level 4 or lower during DTP execution the following ST22 Dump occurs:

Category               ABAP programming error
Runtime Errors         DYN_CALL_METH_REF_IS_INITIAL
Except.                CX_SY_REF_IS_INITIAL
ABAP Program           CL_RSTRAN_TRFN_CMD============CP
Application Component  BW4-DM

Short Text
    Object reference in the dynamic method call is initial.

and contains the following in the part:

How to correct the error

"DYN_CALL_METH_REF_IS_INITIAL" CX_SY_REF_IS_INITIAL
"CL_RSTRAN_TRFN_CMD============CP" bzw. CL_RSTRAN_TRFN_CMD============CM005
"IF_RSBK_CMD_T~TRANSFORM"

• BW/4HANA 2.0 - All releases
• BW/4HANA 2021 - All releases
• BW/4HANA 2023 - All releases
• BW Bridge

Internal session terminated with a runtime error , Transformation path of DTP * is invalid. DTP maintenance not possible , The transformations of the path are incompatible , RSBK*147 , RSTRAN_DB*020, RSO_RES_FRMW*023 , KBA , BW4-DM-DTP , ABAP Orchestration of Data Transfer Process , BW4-DM-ADSO , DataStore Object (Advanced) , BW4-DM-TRFN , SAP HANA execution in Transformation and DTP , DS-BWB-ME-DTP , Data Transfer Process Metadata , BW4-ME-TRFN , Transformation Metadata , BW4-ME-DTP , Data Transfer Process Metadata , DS-BWB-DM-TRFN , SAP HANA execution in Transformation and DTP , DS-BWB-DM-DTP , ABAP Orchestration of Data Transfer Process , BW4-DM-MD , Masterdata , Problem