3447819 - Error "Virtual destination port is not valid" in S/4HANA On-Premise Connection - SAP Datasphere

This KBA applies to SAP Datasphere connections to ABAP-based On-Premise systems (e.g., S/4HANA, ECC, or BW) via SAP Cloud Connector.

The following error occurs for feature data flow and replication flow when validating connection in SAP Datasphere.

Connection "<connection_name>" couldn’t be established.
- Data flows can’t be used because of errors in the connection.
- Replication flows can’t be used because of errors in the connection.

Data Flows: Cause: Failed to retrieve connection xxxxxx::RFC::NamedUser. Server responded with 500
Virtual destination port <port> is not valid
Replication Flows: Cause: Failed to retrieve connection xxxxxx::RFC::NamedUser. Server responded with 500
Virtual destination port <port> is not valid

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SAP Datasphere

"Failed to retrieve connection" "Server responded with 500" , KBA , DS-DI-CON , Connections , Problem