3479260 - Error: "Open request could not be performed due to error: Server Busy Try again later."

When validating connection in SAP Datasphere, the following error occurs:

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Connection "XXX" couldn’t be established. - Data flows can’t be used because of errors in the connection.

Data Flows: Cause: Open request could not be performed due to error: Server Busy Try again later.

Correlation ID: XXXX-XXXX-XXXX-XXXX-XXXX

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The SAP Cloud Connector logs have some logs similar to the following:

2024-01-16 13:32:23,853 -0600#ERROR#com.sap.core.connectivity.tunnel.client.reconnect.AbstractReconnectableClient#notification-client-23-1#          #Connect client to 'connectivitynotification.cf.us10.hana.ondemand.com:443' failed: handshake timed out after 10000ms
2024-01-16 13:33:05,324 -0600#ERROR#com.sap.scc.rt#https-jsse-nio2-8443-exec-10#          #Tunnel account:///29cf9b98-c4b1-4af0-8d0c-83b7ba80f57e/CPITEST connect failed
io.netty.handler.ssl.SslHandshakeTimeoutException: handshake timed out after 10000ms
2024-04-23 00:42:11,293 -0500#ERROR#com.sap.core.connectivity.spi.processing.AbstractProtocolProcessor#tunnel-client-34-1#0xf28e9aa4#Unable to open connection to backend system: error 111 - Connection refused: gt5b4devas01.gst.ibmcloud.local/10.110.18.10:8040

SAP Datasphere

SCC, DS, SAP Cloud Connector , KBA , DS-DI-CON , Connections , Problem